4iir
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4iir| PDB=4iir | SCENE= }} | {{STRUCTURE_4iir| PDB=4iir | SCENE= }} | ||
===Crystal Structure of AMPPNP-bound Human PRPF4B kinase domain=== | ===Crystal Structure of AMPPNP-bound Human PRPF4B kinase domain=== | ||
| + | {{ABSTRACT_PUBMED_24003220}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4iir]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IIR OCA]. | [[4iir]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IIR OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:024003220</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
Revision as of 02:58, 20 September 2013
Contents |
Crystal Structure of AMPPNP-bound Human PRPF4B kinase domain
Template:ABSTRACT PUBMED 24003220
Function
[PRP4B_HUMAN] Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.
About this Structure
4iir is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Gao Q, Mechin I, Kothari N, Guo Z, Deng G, Haas K, McManus J, Hoffmann D, Wang A, Wiederschain D, Rocnik J, Czechtizky W, Chen X, McLean L, Arlt H, Harper D, Liu F, Majid T, Patel V, Lengauer C, Garcia-Echeverria C, Zhang B, Cheng H, Dorsch M, Huang SM. Evaluation of cancer dependence and druggability of PRP4 kinase using cellular, biochemical, and structural approaches. J Biol Chem. 2013 Sep 3. PMID:24003220 doi:10.1074/jbc.M113.473348
