4hwt

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Revision as of 04:07, 20 September 2013

Template:STRUCTURE 4hwt

Crystal structure of human Threonyl-tRNA synthetase bound to a novel inhibitor

Template:ABSTRACT PUBMED 23362938

About this Structure

4hwt is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Teng M, Hilgers MT, Cunningham ML, Borchardt A, Locke JB, Abraham S, Haley G, Kwan BP, Hall C, Hough GW, Shaw KJ, Finn J. Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design. J Med Chem. 2013 Feb 28;56(4):1748-60. doi: 10.1021/jm301756m. Epub 2013 Feb 12. PMID:23362938 doi:10.1021/jm301756m