4c11
From Proteopedia
(Difference between revisions)
m (Protected "4c11" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
{{STRUCTURE_4c11| PDB=4c11 | SCENE= }} | {{STRUCTURE_4c11| PDB=4c11 | SCENE= }} | ||
===Dengue virus RNA dependent RNA polymerase with residues from the NS5 linker region=== | ===Dengue virus RNA dependent RNA polymerase with residues from the NS5 linker region=== | ||
| + | {{ABSTRACT_PUBMED_24025331}} | ||
==Function== | ==Function== | ||
| Line 7: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
[[4c11]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus Dengue virus] and [http://en.wikipedia.org/wiki/Zasmidium_angulare Zasmidium angulare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C11 OCA]. | [[4c11]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus Dengue virus] and [http://en.wikipedia.org/wiki/Zasmidium_angulare Zasmidium angulare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C11 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:024025331</ref><references group="xtra"/><references/> | ||
[[Category: Dengue virus]] | [[Category: Dengue virus]] | ||
[[Category: Zasmidium angulare]] | [[Category: Zasmidium angulare]] | ||
Revision as of 06:55, 29 September 2013
Contents |
Dengue virus RNA dependent RNA polymerase with residues from the NS5 linker region
Template:ABSTRACT PUBMED 24025331
Function
[Q6DLV0_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774]
About this Structure
4c11 is a 2 chain structure with sequence from Dengue virus and Zasmidium angulare. Full crystallographic information is available from OCA.
Reference
- Lim SP, Koh JH, Seh CC, Liew CW, Davidson AD, Chua LS, Chandrasekaran R, Cornvik TC, Shi PY, Lescar J. A crystal structure of the Dengue virus NS5 polymerase delineates inter-domain amino acids residues that enhance its thermostability and de novo initiation activities. J Biol Chem. 2013 Sep 11. PMID:24025331 doi:10.1074/jbc.M113.508606
