4btj
From Proteopedia
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| - | + | {{STRUCTURE_4btj| PDB=4btj | SCENE= }} | |
| + | ===TTBK1 in complex with ATP=== | ||
| + | {{ABSTRACT_PUBMED_24039150}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/TTBK1_HUMAN TTBK1_HUMAN]] Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.<ref>PMID:16923168</ref> | ||
| - | + | ==About this Structure== | |
| + | [[4btj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BTJ OCA]. | ||
| - | + | ==Reference== | |
| + | <ref group="xtra">PMID:024039150</ref><references group="xtra"/><references/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Dekker, N.]] | ||
| + | [[Category: Hillertz, P.]] | ||
| + | [[Category: Schweikart, F.]] | ||
| + | [[Category: Wan, P.]] | ||
| + | [[Category: Wissler, L.]] | ||
| + | [[Category: Xue, Y.]] | ||
| + | [[Category: Zhao, Y.]] | ||
| + | [[Category: Ligand complex]] | ||
| + | [[Category: Structure-kinetics relationship]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 08:10, 29 September 2013
Contents |
TTBK1 in complex with ATP
Template:ABSTRACT PUBMED 24039150
Function
[TTBK1_HUMAN] Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.[1]
About this Structure
4btj is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Xue Y, Wan PT, Hillertz P, Schweikart F, Zhao Y, Wissler L, Dekker N. X-ray Structural Analysis of Tau-Tubulin Kinase 1 and Its Interactions with Small Molecular Inhibitors. ChemMedChem. 2013 Sep 13. doi: 10.1002/cmdc.201300274. PMID:24039150 doi:10.1002/cmdc.201300274
