4bpw
From Proteopedia
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- | + | {{STRUCTURE_4bpw| PDB=4bpw | SCENE= }} | |
+ | ===Crystal structure of human primase bound to UTP=== | ||
+ | {{ABSTRACT_PUBMED_24043831}} | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/PRI1_HUMAN PRI1_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. [[http://www.uniprot.org/uniprot/PRI2_HUMAN PRI2_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. | ||
- | + | ==About this Structure== | |
+ | [[4bpw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BPW OCA]. | ||
- | + | ==Reference== | |
+ | <ref group="xtra">PMID:024043831</ref><references group="xtra"/><references/> | ||
+ | [[Category: Homo sapiens]] | ||
+ | [[Category: Kilkenny, M L.]] | ||
+ | [[Category: Pellegrini, L.]] | ||
+ | [[Category: Perera, R L.]] | ||
+ | [[Category: Dna replication]] | ||
+ | [[Category: Dna-dependent rna polymerase]] | ||
+ | [[Category: Transferase]] |
Revision as of 08:11, 29 September 2013
Contents |
Crystal structure of human primase bound to UTP
Template:ABSTRACT PUBMED 24043831
Function
[PRI1_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. [PRI2_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
About this Structure
4bpw is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Kilkenny ML, Longo MA, Perera RL, Pellegrini L. Structures of human primase reveal design of nucleotide elongation site and mode of Pol alpha tethering. Proc Natl Acad Sci U S A. 2013 Sep 16. PMID:24043831 doi:10.1073/pnas.1311185110