4itc
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4itc| PDB=4itc | SCENE= }} | |
| + | ===Crystal Structure Analysis of the K1 Cleaved Adhesin domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis W83=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/KGP83_PORGN KGP83_PORGN]] Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria (By similarity).[UniProtKB:B2RLK2] | ||
| - | + | ==About this Structure== | |
| - | + | [[4itc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Porphyromonas_gingivalis Porphyromonas gingivalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ITC OCA]. | |
| - | + | [[Category: Gingipain K]] | |
| + | [[Category: Porphyromonas gingivalis]] | ||
| + | [[Category: Collyer, C A.]] | ||
| + | [[Category: Ganuelas, L A.]] | ||
| + | [[Category: Hunter, N.]] | ||
| + | [[Category: Li, N.]] | ||
| + | [[Category: Beta sandwich]] | ||
| + | [[Category: Calcium binding]] | ||
| + | [[Category: Cell invasion]] | ||
| + | [[Category: Cleaved adhesin family]] | ||
| + | [[Category: Cysteine protease]] | ||
| + | [[Category: Hemagglutinin domain]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Lys-gingipain]] | ||
| + | [[Category: Membrane surface]] | ||
Revision as of 08:18, 29 September 2013
Crystal Structure Analysis of the K1 Cleaved Adhesin domain of Lys-gingipain (Kgp) from Porphyromonas gingivalis W83
Function
[KGP83_PORGN] Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria (By similarity).[UniProtKB:B2RLK2]
About this Structure
4itc is a 1 chain structure with sequence from Porphyromonas gingivalis. Full crystallographic information is available from OCA.
