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2g70

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[[Image:2g70.png|left|200px]]
 
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{{STRUCTURE_2g70| PDB=2g70 | SCENE= }}
{{STRUCTURE_2g70| PDB=2g70 | SCENE= }}
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===Structure of human PNMT in complex with inhibitor 3-hydroxymethyl-7-nitro-THIQ and AdoMet (SAM)===
===Structure of human PNMT in complex with inhibitor 3-hydroxymethyl-7-nitro-THIQ and AdoMet (SAM)===
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{{ABSTRACT_PUBMED_17845018}}
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{{ABSTRACT_PUBMED_17845018}}
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==Function==
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[[http://www.uniprot.org/uniprot/PNMT_HUMAN PNMT_HUMAN]] Converts noradrenaline to adrenaline.
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:017845018</ref><ref group="xtra">PMID:016710295</ref><references group="xtra"/>
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<ref group="xtra">PMID:017845018</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phenylethanolamine N-methyltransferase]]
[[Category: Phenylethanolamine N-methyltransferase]]

Revision as of 05:59, 2 October 2013

Template:STRUCTURE 2g70

Contents

Structure of human PNMT in complex with inhibitor 3-hydroxymethyl-7-nitro-THIQ and AdoMet (SAM)

Template:ABSTRACT PUBMED 17845018

Function

[PNMT_HUMAN] Converts noradrenaline to adrenaline.

About this Structure

2g70 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Gee CL, Drinkwater N, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Enzyme adaptation to inhibitor binding: a cryptic binding site in phenylethanolamine N-methyltransferase. J Med Chem. 2007 Oct 4;50(20):4845-53. Epub 2007 Sep 11. PMID:17845018 doi:10.1021/jm0703385

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OCA

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