4key

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
{{STRUCTURE_4key| PDB=4key | SCENE= }}
{{STRUCTURE_4key| PDB=4key | SCENE= }}
===Structure of P450 BM3 A82F F87V in complex with omeprazole===
===Structure of P450 BM3 A82F F87V in complex with omeprazole===
 +
{{ABSTRACT_PUBMED_23828198}}
==Function==
==Function==
Line 7: Line 8:
==About this Structure==
==About this Structure==
[[4key]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEY OCA].
[[4key]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEY OCA].
 +
 +
==See Also==
 +
*[[Cytochrome P450|Cytochrome P450]]
 +
 +
==Reference==
 +
<ref group="xtra">PMID:023828198</ref><references group="xtra"/><references/>
[[Category: Bacillus megaterium]]
[[Category: Bacillus megaterium]]
[[Category: Leys, D.]]
[[Category: Leys, D.]]

Revision as of 06:11, 2 October 2013

Template:STRUCTURE 4key

Contents

Structure of P450 BM3 A82F F87V in complex with omeprazole

Template:ABSTRACT PUBMED 23828198

Function

[CPXB_BACME] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450.

About this Structure

4key is a 2 chain structure with sequence from Bacillus megaterium. Full crystallographic information is available from OCA.

See Also

Reference

  • Butler CF, Peet C, Mason AE, Voice MW, Leys D, Munro AW. Key Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate Bias. J Biol Chem. 2013 Aug 30;288(35):25387-99. doi: 10.1074/jbc.M113.479717. Epub, 2013 Jul 3. PMID:23828198 doi:10.1074/jbc.M113.479717

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4key"
Personal tools