4hp2

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'''Unreleased structure'''
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{{STRUCTURE_4hp2| PDB=4hp2 | SCENE= }}
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===Invariom refinement of a new dimeric monoclinic 2 solvate of thiostrepton at 0.64 angstrom resolution===
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{{ABSTRACT_PUBMED_23897476}}
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The entry 4hp2 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/THCL_STRAJ THCL_STRAJ]] Has bacteriocidal activity. Inhibits bacterial protein biosynthesis by acting on the elongation factor Tu (EF-Tu) (By similarity).
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Authors: Proepper, K., Holstein, J.J., Huebschle, C.B., Bond, C.S., Dittrich, B.
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==About this Structure==
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[[4hp2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_azureus Streptomyces azureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HP2 OCA].
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Description: Invariom refinement of a new dimeric monoclinic 2 solvate of thiostrepton at 0.64 angstrom resolution
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==Reference==
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<ref group="xtra">PMID:023897476</ref><references group="xtra"/><references/>
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[[Category: Streptomyces azureus]]
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[[Category: Bond, C S.]]
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[[Category: Dittrich, B.]]
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[[Category: Holstein, J J.]]
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[[Category: Huebschle, C B.]]
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[[Category: Proepper, K.]]
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[[Category: Antibacterial]]
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[[Category: Antibiotic]]
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[[Category: Oxazole]]
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[[Category: Ribosome]]
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[[Category: Thiazole]]
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[[Category: Thiazoline]]
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[[Category: Thiopeptide]]
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[[Category: Translation inhibition]]

Revision as of 07:22, 2 October 2013

Template:STRUCTURE 4hp2

Contents

Invariom refinement of a new dimeric monoclinic 2 solvate of thiostrepton at 0.64 angstrom resolution

Template:ABSTRACT PUBMED 23897476

Function

[THCL_STRAJ] Has bacteriocidal activity. Inhibits bacterial protein biosynthesis by acting on the elongation factor Tu (EF-Tu) (By similarity).

About this Structure

4hp2 is a 2 chain structure with sequence from Streptomyces azureus. Full crystallographic information is available from OCA.

Reference

  • Propper K, Holstein JJ, Hubschle CB, Bond CS, Dittrich B. Invariom refinement of a new monoclinic solvate of thiostrepton at 0.64 A resolution. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1530-9. doi:, 10.1107/S0907444913010664. Epub 2013 Jul 19. PMID:23897476 doi:10.1107/S0907444913010664

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