4lfx

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'''Unreleased structure'''
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{{STRUCTURE_4lfx| PDB=4lfx | SCENE= }}
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===X-ray structure of the adduct between hen egg white lysozyme and Auoxo6, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers===
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{{ABSTRACT_PUBMED_24045294}}
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The entry 4lfx is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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Authors: Vergara, A., Merlino, A.
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==About this Structure==
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[[4lfx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LFX OCA].
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Description: X-ray structure of the adduct between hen egg white lysozyme and Auoxo6, a dinuclear gold(III) complexes with -dioxo bridges linking the two metal centers
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==Reference==
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<ref group="xtra">PMID:024045294</ref><references group="xtra"/><references/>
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[[Category: Gallus gallus]]
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[[Category: Lysozyme]]
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[[Category: Merlino, A.]]
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[[Category: Vergara, A.]]
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[[Category: Hydrolase]]

Revision as of 07:25, 2 October 2013

Template:STRUCTURE 4lfx

Contents

X-ray structure of the adduct between hen egg white lysozyme and Auoxo6, a dinuclear gold(III) complex with -dioxo bridges linking the two metal centers

Template:ABSTRACT PUBMED 24045294

Function

[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]

About this Structure

4lfx is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

  • Messori L, Scaletti F, Massai L, Cinellu MA, Gabbiani C, Vergara A, Merlino A. The mode of action of anticancer gold-based drugs: a structural perspective. Chem Commun (Camb). 2013 Sep 18. PMID:24045294 doi:10.1039/c3cc46400h
  1. ↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021

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