4kp7

(Difference between revisions)

Revision as of 07:29, 2 October 2013

4kp7 is a 2 chain structure with sequence from Plasmodium falciparum hb3. Full crystallographic information is available from OCA.

Kunfermann A, Lienau C, Illarionov B, Held J, Grawert T, Behrendt CT, Werner P, Hahn S, Eisenreich W, Riederer U, Mordmuller B, Bacher A, Fischer M, Groll M, Kurz T. IspC as target for antiinfective drug discovery: Synthesis, enantiomeric separation and structural biology of fosmidomycin thia-isosters. J Med Chem. 2013 Sep 13. PMID:24032981 doi:10.1021/jm4012559

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-'''Unreleased structure'''
+{{STRUCTURE_4kp7|  PDB=4kp7  |  SCENE=  }}
+===Structure of Plasmodium IspC in complex with a beta-thia-isostere derivative of Fosmidomycin===
+{{ABSTRACT_PUBMED_24032981}}
-The entry 4kp7 is ON HOLD  until Paper Publication
+==About this Structure==
+[[4kp7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_hb3 Plasmodium falciparum hb3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KP7 OCA].
-Authors: Kunfermann, A., Bacher, A., Groll, M.
+==Reference==
+<ref group="xtra">PMID:024032981</ref><references group="xtra"/><references/>
-Description: Structure of Plasmodium IspC in complex with a beta-thia-isostere derivative of Fosmidomycin
+[[Category: 1-deoxy-D-xylulose-5-phosphate reductoisomerase]]
+[[Category: Plasmodium falciparum hb3]]
+[[Category: Bacher, A.]]
+[[Category: Groll, M.]]
+[[Category: Kunfermann, A.]]
+[[Category: Apicoplast]]
+[[Category: Drug optimization]]
+[[Category: Dxp pathway]]
+[[Category: Malaria]]
+[[Category: Nadph binding]]
+[[Category: Non-covalent inhibition]]
+[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+[[Category: Reductoisomerase]]
+[[Category: Rossmann fold]]
+[[Category: Tuberculosis]]