4fl9
From Proteopedia
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| - | + | {{STRUCTURE_4fl9| PDB=4fl9 | SCENE= }} | |
| + | ===Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/HSP7C_BOVIN HSP7C_BOVIN]] Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex (By similarity). | ||
| - | + | ==About this Structure== | |
| - | + | [[4fl9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FL9 OCA]. | |
| - | + | [[Category: Bos taurus]] | |
| + | [[Category: Grimm, C.]] | ||
| + | [[Category: Heat shock protein]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 07:32, 2 October 2013
Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution
Function
[HSP7C_BOVIN] Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex (By similarity).
About this Structure
4fl9 is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
