4j80

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{{STRUCTURE_4j80| PDB=4j80 | SCENE= }}
{{STRUCTURE_4j80| PDB=4j80 | SCENE= }}
===Thermus thermophilus DnaJ===
===Thermus thermophilus DnaJ===
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{{ABSTRACT_PUBMED_23897477}}
==Function==
==Function==
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==Reference==
==Reference==
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<references group="xtra"/><references/>
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<ref group="xtra">PMID:023897477</ref><references group="xtra"/><references/>
[[Category: Thermus thermophilus hb8]]
[[Category: Thermus thermophilus hb8]]
[[Category: Barends, T R.M.]]
[[Category: Barends, T R.M.]]

Revision as of 04:52, 10 October 2013

Template:STRUCTURE 4j80

Contents

Thermus thermophilus DnaJ

Template:ABSTRACT PUBMED 23897477

Function

[DNAJ2_THET8] Does not influence ATP binding or hydrolysis nor ADP release. Exerts influence on the interaction of DnaK with substrates; in the presence of DafA, DnaJ inhibits substrate binding, and substrate already bound to DnaK is displaced by DnaJ and DafA.[1]

About this Structure

4j80 is a 4 chain structure with sequence from Thermus thermophilus hb8. Full crystallographic information is available from OCA.

Reference

  • Barends TR, Brosi RW, Steinmetz A, Scherer A, Hartmann E, Eschenbach J, Lorenz T, Seidel R, Shoeman RL, Zimmermann S, Bittl R, Schlichting I, Reinstein J. Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1540-52. doi:, 10.1107/S0907444913010640. Epub 2013 Jul 19. PMID:23897477 doi:http://dx.doi.org/10.1107/S0907444913010640
  1. Klostermeier D, Seidel R, Reinstein J. The functional cycle and regulation of the Thermus thermophilus DnaK chaperone system. J Mol Biol. 1999 Apr 2;287(3):511-25. PMID:10092456 doi:10.1006/jmbi.1999.2636

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