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4jcj

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{{STRUCTURE_4jcj| PDB=4jcj | SCENE= }}
{{STRUCTURE_4jcj| PDB=4jcj | SCENE= }}
===Crystal structure of Isl1 LIM domains with Ldb1 LIM-interaction domain===
===Crystal structure of Isl1 LIM domains with Ldb1 LIM-interaction domain===
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{{ABSTRACT_PUBMED_23750000}}
==Function==
==Function==
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==About this Structure==
==About this Structure==
[[4jcj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JCJ OCA].
[[4jcj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JCJ OCA].
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==Reference==
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<ref group="xtra">PMID:023750000</ref><references group="xtra"/><references/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Gadd, M S.]]
[[Category: Gadd, M S.]]

Revision as of 05:04, 10 October 2013

Template:STRUCTURE 4jcj

Contents

Crystal structure of Isl1 LIM domains with Ldb1 LIM-interaction domain

Template:ABSTRACT PUBMED 23750000

Function

[ISL1_MOUSE] Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1.

About this Structure

4jcj is a 3 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Gadd MS, Jacques DA, Nisevic I, Craig VJ, Kwan AH, Guss JM, Matthews JM. A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions. J Biol Chem. 2013 Jul 26;288(30):21924-35. doi: 10.1074/jbc.M113.478586. Epub, 2013 Jun 9. PMID:23750000 doi:http://dx.doi.org/10.1074/jbc.M113.478586

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