4c59

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "4c59" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4c59| PDB=4c59 | SCENE= }}
 +
===Structure of GAK kinase in complex with nanobody (NbGAK_4)===
-
The entry 4c59 is ON HOLD
+
==Function==
 +
[[http://www.uniprot.org/uniprot/GAK_HUMAN GAK_HUMAN]] Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.<ref>PMID:10625686</ref>
-
Authors: Chaikuad, A., Keates, T., Allerston, C.K., Gileadi, O., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Knapp, S., Muller-Knapp, S.
+
==About this Structure==
 +
[[4c59]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C59 OCA].
-
Description: Structure of GAK kinase in complex with nanobody (NbGAK_4)
+
==Reference==
 +
<references group="xtra"/><references/>
 +
[[Category: Homo sapiens]]
 +
[[Category: Non-specific serine/threonine protein kinase]]
 +
[[Category: Allerston, C K.]]
 +
[[Category: Arrowsmith, C H.]]
 +
[[Category: Bountra, C.]]
 +
[[Category: Chaikuad, A.]]
 +
[[Category: Delft, F von.]]
 +
[[Category: Edwards, A M.]]
 +
[[Category: Gileadi, O.]]
 +
[[Category: Keates, T.]]
 +
[[Category: Knapp, S.]]
 +
[[Category: Muller-Knapp, S.]]
 +
[[Category: Activation]]
 +
[[Category: Conformational plasticity]]
 +
[[Category: Kinase]]
 +
[[Category: Transferase]]

Revision as of 06:35, 10 October 2013

Template:STRUCTURE 4c59

Contents

Structure of GAK kinase in complex with nanobody (NbGAK_4)

Function

[GAK_HUMAN] Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.[1]

About this Structure

4c59 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. ↑ Greener T, Zhao X, Nojima H, Eisenberg E, Greene LE. Role of cyclin G-associated kinase in uncoating clathrin-coated vesicles from non-neuronal cells. J Biol Chem. 2000 Jan 14;275(2):1365-70. PMID:10625686

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4c59"
Personal tools