2rs6

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[[Image:2rs6.jpg|left|200px]]
 
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{{STRUCTURE_2rs6| PDB=2rs6 | SCENE= }}
{{STRUCTURE_2rs6| PDB=2rs6 | SCENE= }}
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===Solution structure of the N-terminal dsRBD from RNA helicase A===
===Solution structure of the N-terminal dsRBD from RNA helicase A===
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{{ABSTRACT_PUBMED_22454253}}
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==Function==
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[[http://www.uniprot.org/uniprot/DHX9_MOUSE DHX9_MOUSE]] Component of the CRD-mediated complex that promotes MYC mRNA stability. Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alterations of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 (By similarity).
==About this Structure==
==About this Structure==
[[2rs6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RS6 OCA].
[[2rs6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RS6 OCA].
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==Reference==
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<ref group="xtra">PMID:022454253</ref><references group="xtra"/><references/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: RNA helicase]]
[[Category: RNA helicase]]

Revision as of 06:47, 16 October 2013

Template:STRUCTURE 2rs6

Contents

Solution structure of the N-terminal dsRBD from RNA helicase A

Template:ABSTRACT PUBMED 22454253

Function

[DHX9_MOUSE] Component of the CRD-mediated complex that promotes MYC mRNA stability. Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alterations of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 (By similarity).

About this Structure

2rs6 is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA.

Reference

  • Nagata T, Tsuda K, Kobayashi N, Shirouzu M, Kigawa T, Guntert P, Yokoyama S, Muto Y. Solution structures of the double-stranded RNA-binding domains from RNA helicase A. Proteins. 2012 Jun;80(6):1699-706. doi: 10.1002/prot.24059. Epub 2012 Mar 27. PMID:22454253 doi:http://dx.doi.org/10.1002/prot.24059

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