4doh

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[[Image:4doh.png|left|200px]]
 
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{{STRUCTURE_4doh| PDB=4doh | SCENE= }}
{{STRUCTURE_4doh| PDB=4doh | SCENE= }}
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===IL20/IL201/IL20R2 Ternary Complex===
===IL20/IL201/IL20R2 Ternary Complex===
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{{ABSTRACT_PUBMED_22802649}}
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{{ABSTRACT_PUBMED_22802649}}
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==Function==
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[[http://www.uniprot.org/uniprot/IL20_HUMAN IL20_HUMAN]] Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3.
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:022802649</ref><references group="xtra"/>
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<ref group="xtra">PMID:022802649</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Logsdon, N J.]]
[[Category: Logsdon, N J.]]

Revision as of 06:53, 16 October 2013

Template:STRUCTURE 4doh

Contents

IL20/IL201/IL20R2 Ternary Complex

Template:ABSTRACT PUBMED 22802649

Function

[IL20_HUMAN] Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3.

About this Structure

4doh is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Logsdon NJ, Deshpande A, Harris BD, Rajashankar KR, Walter MR. Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12704-9. Epub 2012 Jul 16. PMID:22802649 doi:10.1073/pnas.1117551109

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