4j0l

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-	'''Unreleased structure'''	+	{{STRUCTURE_4j0l| PDB=4j0l | SCENE= }}
		+	===Crystal Structure of a Family GH19 Chitinase (W72A/E67Q mutant) from rye seeds in complex with two (GlcNAc)4 molecules===
		+	{{ABSTRACT_PUBMED_23871710}}
-	The entry 4j0l is ON HOLD until Paper Publication	+	==Function==
		+	[[http://www.uniprot.org/uniprot/CHIC_SECCE CHIC_SECCE]] Defense against chitin containing fungal pathogens. Binds the hyphal tips of fungi and degrades nascent chitin.<ref>PMID:11999399</ref> <ref>PMID:11826968</ref> <ref>PMID:12092848</ref>
-	Authors: Umemoto, N., Numata, T., Ohnuma, T., Fukamizo, T.	+	==About this Structure==
		+	[[4j0l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Secale_cereale Secale cereale]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J0L OCA].
-	Description: Crystal Structure of a Family GH19 Chitinase (W72A/E67Q mutant) from rye seeds in complex with two (GlcNAc)4 molecules	+	==Reference==
		+	<ref group="xtra">PMID:023871710</ref><references group="xtra"/><references/>
		+	[[Category: Chitinase]]
		+	[[Category: Secale cereale]]
		+	[[Category: Fukamizo, T.]]
		+	[[Category: Numata, T.]]
		+	[[Category: Ohnuma, T.]]
		+	[[Category: Umemoto, N.]]
		+	[[Category: Carbohydrate]]
		+	[[Category: Chitinase]]
		+	[[Category: Hydrolase]]

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Revision as of 07:59, 16 October 2013

Template:STRUCTURE 4j0l

Contents 1 Crystal Structure of a Family GH19 Chitinase (W72A/E67Q mutant) from rye seeds in complex with two (GlcNAc)4 molecules 2 Function 3 About this Structure 4 Reference

Crystal Structure of a Family GH19 Chitinase (W72A/E67Q mutant) from rye seeds in complex with two (GlcNAc)4 molecules

Template:ABSTRACT PUBMED 23871710

Function

[CHIC_SECCE] Defense against chitin containing fungal pathogens. Binds the hyphal tips of fungi and degrades nascent chitin.^{[1] [2] [3]}

About this Structure

4j0l is a 1 chain structure with sequence from Secale cereale. Full crystallographic information is available from OCA.

Reference

• Ohnuma T, Umemoto N, Kondo K, Numata T, Fukamizo T. Complete subsite mapping of a "loopful" GH19 chitinase from rye seeds based on its crystal structure. FEBS Lett. 2013 Aug 19;587(16):2691-7. doi: 10.1016/j.febslet.2013.07.008. Epub, 2013 Jul 18. PMID:23871710 doi:http://dx.doi.org/10.1016/j.febslet.2013.07.008

1. ↑ Ohnuma T, Yagi M, Yamagami T, Taira T, Aso Y, Ishiguro M. Molecular cloning, functional expression, and mutagenesis of cDNA encoding rye (Secale cereale) seed chitinase-c. Biosci Biotechnol Biochem. 2002 Feb;66(2):277-84. PMID:11999399
2. ↑ Taira T, Yamagami T, Aso Y, Ishiguro M, Ishihara M. Localization, accumulation, and antifungal activity of chitinases in rye (Secale cereale) seed. Biosci Biotechnol Biochem. 2001 Dec;65(12):2710-8. PMID:11826968
3. ↑ Taira T, Ohnuma T, Yamagami T, Aso Y, Ishiguro M, Ishihara M. Antifungal activity of rye (Secale cereale) seed chitinases: the different binding manner of class I and class II chitinases to the fungal cell walls. Biosci Biotechnol Biochem. 2002 May;66(5):970-7. PMID:12092848