Ribosomal protein S3

From Proteopedia

Revision as of 09:31, 16 October 2013

Template:STRUCTURE 3kc4

Ribosomal protein S3 (RPS3) is one of the 22 proteins which belong to the of the bacterial ribosome. It is known to be involved in the binding of initiator tRNA fMet. The images at the left and at the right correspond to one representative RPS3, i.e. the crystal structure of Ribosomal protein S3 from Escherichia coli (3kc4).

3D Structures of Ribosomal protein S3

Updated on 16-October-2013

S3 in small ribosomal subunit

2zm6, 1n36, 1j5e, 3oto - TtRPS3 in 30S ribosomal subunit+THX+16S RRNA – Thermus thermophilus
2vqe, 2vqf, 2uuc, 2e5l, 2uu9, 2uua, 2uub, 3pyn, 3pyq, 3pys, 3pyu - TtRPS3 in 30S ribosomal subunit+16S RRNA+RNA fragment
3kc4 – EcRPS3 in 30S ribosomal subunit - Escherichia coli
3i1m, 3i1o, 3df1, 3df3, 2vho, 2vhp, 2avy, 2aw7, 1pnx - EcRPS3 in 30S ribosomal subunit+16S RRNA
1i94, 1fka, 3uxs, 3uxt, 4dr1 - TtRPS3 in 30S ribosomal subunit+16S RRNA
4duy, 4duz, 4dv0, 4dv1, 4dv2, 4dv3, 4dv4, 4dv5, 4dv6, 4dv7 – TtRPS3 in 30S ribosomal subunit+16S RRNA (mutant)
4dr4, 4b3m, 4b3r, 4b3s, 4b3t – TtRPS3 in 30S ribosomal subunit+16S RRNA + mRNA
1p87 - EcRPS3 in 30S ribosomal subunit+16S RRNA – Cryo-EM
3bbn - RPS3 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach

S3 in small + large ribosomal subunit

1ml5 - EcRPS3 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA
Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM

S3 in small ribosomal subunit+ chain release factor (RF)

3mr8, 3ms0 – TtRPS3 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA
3d5a, 3d5c - TtRPS3 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA
3zvo - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA Met +mRNA +16S RRNA+chain release factor 3
2b64 - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1
2b9m - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2
2x9r, 2x9t, 2wh1, 2wh3 - TtRPS2 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA
3f1e, 3f1g - TtRPS3 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA
4kfh, 4kfk – TtRPS3 in 30S ribosomal subunit+16S RRNA+ RF-2 + mRNA+ P-site tRNA fMet

S3 in small ribosomal subunit+tRNA+mRNA

2hgi - TtRPS3 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet
4l6k, 4l6m – TtRPS3 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA
2hgp, 2i2p, 2i2u - TtRPS3 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA
3t1h, 3t1y - TtRPS3 in 30S ribosomal subunit+16S RRNA+tRNA Lys +mRNA
3tvf, 3tvg, 3uyd, 3uyf - TtRPS3 in 30S ribosomal subunit+16S RRNA+tRNA Leu + tRNA fMet + mRNA
3zn7, 3znd – TtRPS3 in 30S ribosomal subunit+16S RRNA+A-site tRNA Ile agmatidine + E-site tRNA Ile agmatidine + mRNA
3uz6, 3uz7, 3uzg, 3uzi - TtRPS3 in 30S ribosomal subunit+16S RRNA+tRNA Tyr + tRNA fMet + mRNA
2hgr, 3v6u, 3v6v, 4ej9, 4eja - TtRPS3 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA
1yl4 – TtRPS3 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator
1pns - EcRPS3 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA
3j0u, 3j0v, 3j0x, 3j0z, 3j10, 3j20 – EcRPS3 in 30S ribosomal subunit+ A-site tRNA + P-site tRNA +16S RRNA+mRNA – Cryo-EM
3j13 – EcRPS3 in 30S ribosomal subunit+ P-site tRNA +16S RRNA+mRNA – Cryo-EM
1xnq, 1xnr- TtRPS3 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA
4gkj, 4gkk – TtRPS3 in 30S ribosomal subunit +16S RRNA +THX + mRNA + tRNA Met
4jv5, 4jya, 4k0k, 4k0l – TtRPS3 in 30S ribosomal subunit +16S RRNA +THX + mRNA + ASL-tRNA

S3 in small ribosomal subunit+A-site tRNA

2uxd, 2uxc - TtRPS3 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA
1n32, 1n33 - TtRPS3 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA
1n34 - TtRPS3 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA
1xmo, 1xmq - TtRPS3 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA
2uxb - TtRPS3 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA

S3 in small ribosomal subunit+P-site tRNA

3i8g - TtRPS3 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA
3i8h, 3i9b, 3i9d - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA
1ibk - TtRPS3 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA
2wwl - EcRPS3 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - Escherichia coli
3i1q - EcRPS3 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA
3i1s, 3i1z, 3i21 - EcRPS3 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA

S3 in small ribosomal subunit+A-site tRNA+P-site tRNA

1ibl, 1ibm - TtRPS3 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA

S3 in small ribosomal subunit+P-site tRNA+E-site tRNA

2ow8 - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA
2b9o - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA
2qnh - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA
2wdg, 2wdh, 2wdk, 2wdm - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe

S3 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA

2gy9, 2gyb - EcRPS3 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM
1jgo, 1jgp, 1jgq, 1gix - TtRPS3 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA
4k0p – TtRPS3 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA +mRNA +16S RRNA 3e1a, 3e1c - EcRPS3 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA

S3 in small ribosomal subunit + antibiotics

1i95, 1i97, 2hhh, 2f4v, 3oge, 3ogy, 3ohc, 3ohd, 3ohy, 3oi0, 3oi2, 3oi4, 4dr3 - TtRPS3 in 30S ribosomal subunit+16S RRNA+antibiotic
1hnw, 1hnx, 1hnz, 1fjg, 4aqy, 4dr5, 4dr7, 4khp - TtRPS3 in 30S ribosomal subunit+16S RRNA+mRNA fragment+antibiotic
2qbb, 2qb9, 1vs5, 1vs7, 2qan, 2qal, 2qou, 2qow, 2qoy, 2qp0, 2z4k, 2z4m,3oaq, 3oar, 3ofa, 3ofb, 3ofo, 3ofp, 3ofx, 3ofy, 3or9, 3ora- EcRPS3 in 30S ribosomal subunit+16S RRNA+antibiotic
3sfs – EcRPS3 in 30S ribosomal subunit+16S RRNA+ mRNA + RF-3 + antibiotic
4gaq, 4gas – EcRPS3 in 30S ribosomal subunit+16S RRNA+ mRNA + antibiotic
2j00, 2j02 - TtRPS3 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA
3knl, 3knm, 3knn, 3kno, 4knj, 4knh - TtRPS3 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+ antibiotics
3uz3, 3uz4 - TtRPS3 in 30S ribosomal subunit+16S RRNA+tRNA Leu + tRNA fMet + mRNA + paromomycin
4g5k, 4g5m, 4g5t, 4g5v – TtRPS3 in 30S ribosomal subunit+16S RRNA + tRNA fMet + mRNA + antibiotics
3uzl, 3uzm - TtRPS3 in 30S ribosomal subunit+16S RRNA+tRNA Tyr + tRNA fMet + mRNA + paromomycin

S3 in small ribosomal subunit + ribosome recycling factor

2qbd, 2qbf - EcRPS3 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor
3r8n, 3r8o, 4gd1, 4gd2 – EcRPS3 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA
2qbh, 2qbj - EcRPS3 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin
2v46, 2v48 - TtRPS3 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet

S3 in small ribosomal subunit + elongation factor

2wri, 2wrk - TtRPS3 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G
2wrn, 2wrq - TtRPS3 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4
3fic - TtRPS3 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A
4abr - TtRPS3 in 30S ribosomal subunit+THX + E/P-site tRNA fMet +mRNA codon+16S RRNA+elongation factor TU
2y0u, 2y0w, 2y0y, 2y10, 2y12, 2y14, 2y16, 2y18 - TtRPS2 in 30S subunit+THX+A-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU
3fih - EcRPS3 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU
3izv – EcRPS3 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU
3j18 - EcRPS3 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+ mRNA + SSRA-binding protein + formyl-Met specific initiator tRNA + elongation factor G – Cryo-EM
3izw – EcRPS3 in 30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU
3huw, 3huy - TtRPS3 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P
1s1h - RPS3 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast
4b8f, 4b8h – TtRPS3 in 30S ribosomal subunit+THX+RNA+mRNA +16S RRNA+elongation factor G
4btc, 4kdg, 4kdj – TtRPS3 in 30S ribosomal subunit+THX+RNA +16S RRNA+elongation factor G
4juw – TtRPS3 in 30S ribosomal subunit+THX+ tRNA Phe +16S RRNA + mRNA +elongation factor G
4kbt, 4kbv, 4kcy, 4kd0, 4kd8, 4kda – TtRPS3 in 30S ribosomal subunit+THX+ tRNA Met +16S RRNA + mRNA + viomycin + elongation factor G
4kiy, 4kj0, 4kj2, 4kj4, 4kj6, 4kj8, 4kja, 4kjc – EcRPS3 in 30S ribosomal subunit +16S RRNA + viomycin + elongation factor G

S3 in small ribosomal subunit + translation initiation factor

1i96 - TtRPS3 in 30S ribosomal subunit+THX+IF3+16S RRNA
1hr0 - TtRPS3 in 30S ribosomal subunit+THX+IF+16S RRNA

S3 in small ribosomal subunit + various proteins

3kiq, 3kis, 3kiu, 3kix - TtRPS3 in 30S ribosomal subunit+toxin RelE+16S RRNA
1voq, 1vos, 1vov, 1vox, 1voz - EcRPS3 in 30S ribosomal subunit+protein Y+16S RRNA
3j36 – EcRPS3 in 30S ribosomal subunit+ tetracycline resistance protein +16S RRNA + mRNA + P-tRNA – Cryo-EM
4dh9, 4dhb - TtRPS3 in 30S ribosomal subunit +16S RRNA+mRNA+P-site tRNA fMet +THX + YAEJ
3j00 – EcRPS3 + 16S RRNA + FTSQ + apolipoprotein A-I
2ykr – EcRPS3 + 16S RRNA + GMPPNP + GTPase RSGA
4a2i – EcRPS3 + 16S RRNA + GTPase RSGA – Cryo EM
3uoq - EcRPS3 + 16S RRNA + mRNA + peptide chain release factor
4adv - EcRPS3 + 16S RRNA + methyltransferase – Cryo EM
3v22, 3v24, 3v26, 3v28 – TtRPS3 in 30S ribosomal subunit +16S RRNA +THX + modulation factor
3v2c, 3v2e – TtRPS3 in 30S ribosomal subunit +16S RRNA +THX + ribosome-associated inhibitor

S3 in small 40S ribosomal subunit + various proteins

3jyv - TlRPS3 in 40S ribosomal subunit+RACK1+S19E+P-site tRNA – Thermomyces lanuginosus
2xzm, 2xzn - RPS2 in 40S subunit+RACK1 - Tetrahymena thermophila
3izb - yRPS3 in 40S ribosomal subunit+ RACK1 – Cryo-EM
3u5c, 3u5g - yRPS3 in 40S ribosomal subunit+ RACK1 + suppressor protein SMT1
3o2z, 3o30 – yRPS3 in 40S ribosomal subunit+ RACK1
3iz6 – RPS3 in 40S ribosomal subunit+RACK1 - wheat
3j38 – RPS3 in 40S ribosomal subunit + EF-2 + guanine nucleotide-binding protein – Drosophila melanogaster – Cryo-EM
3j3a – RPS3 in 40S ribosomal subunit + EF-2 + guanine nucleotide-binding protein – human – Cryo-EM
4kzx - rRPS2 in 40S ribosomal subunit+ RACK1 + EIF1 – rabbit – Cryo-EM
4kzy – rRPS3 in 40S ribosomal subunit+ RACK1 + EIF1 + EIF1A – Cryo-EM
4kzz – rRPS3 in 40S ribosomal subunit+ RACK1 + EIF1A + initiator tRNA – Cryo-EM