4i9m
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4i9m| PDB=4i9m | SCENE= }} | {{STRUCTURE_4i9m| PDB=4i9m | SCENE= }} | ||
===Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus bound to HEPES=== | ===Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus bound to HEPES=== | ||
| + | {{ABSTRACT_PUBMED_23576432}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
| - | [[4i9m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[4i9m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cylindrocarpon_theobromicola Cylindrocarpon theobromicola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I9M OCA]. |
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023576432</ref><references group="xtra"/><references/> | ||
| + | [[Category: Cylindrocarpon theobromicola]] | ||
[[Category: Phosphatidylinositol diacylglycerol-lyase]] | [[Category: Phosphatidylinositol diacylglycerol-lyase]] | ||
| - | [[Category: Staphylococcus aureus subsp. aureus str. newman]] | ||
[[Category: Cheng, J.]] | [[Category: Cheng, J.]] | ||
[[Category: Gershenson, A.]] | [[Category: Gershenson, A.]] | ||
Revision as of 05:23, 23 October 2013
Contents |
Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus bound to HEPES
Template:ABSTRACT PUBMED 23576432
Function
[PLC_STAAE] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor.
About this Structure
4i9m is a 1 chain structure with sequence from Cylindrocarpon theobromicola. Full crystallographic information is available from OCA.
Reference
- Cheng J, Goldstein R, Gershenson A, Stec B, Roberts MF. The cation-pi box is a specific phosphatidylcholine membrane targeting motif. J Biol Chem. 2013 May 24;288(21):14863-73. doi: 10.1074/jbc.M113.466532. Epub, 2013 Apr 10. PMID:23576432 doi:http://dx.doi.org/10.1074/jbc.M113.466532
