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4kgb

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4kgb| PDB=4kgb | SCENE= }}
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===Structure of succinyl-CoA: 3-ketoacid CoA transferase from Drosophila melanogaster===
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{{ABSTRACT_PUBMED_24100554}}
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The entry 4kgb is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/Q9W058_DROME Q9W058_DROME]] Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity).[PIRNR:PIRNR000858]
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Authors: Wang, Y.C., Shi, Z.B., Zhang, M.
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==About this Structure==
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[[4kgb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KGB OCA].
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Description: Structure of succinyl-CoA: 3-ketoacid CoA transferase from Drosophila melanogaster
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==Reference==
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<ref group="xtra">PMID:024100554</ref><references group="xtra"/><references/>
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[[Category: 3-oxoacid CoA-transferase]]
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[[Category: Drosophila melanogaster]]
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[[Category: Shi, Z B.]]
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[[Category: Wang, Y C.]]
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[[Category: Zhang, M.]]
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[[Category: Ketone body catabolic process]]
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[[Category: Protein fold]]
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[[Category: Transferase]]

Revision as of 06:44, 23 October 2013

Template:STRUCTURE 4kgb

Contents

Structure of succinyl-CoA: 3-ketoacid CoA transferase from Drosophila melanogaster

Template:ABSTRACT PUBMED 24100554

Function

[Q9W058_DROME] Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity).[PIRNR:PIRNR000858]

About this Structure

4kgb is a 2 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

Reference

  • Zhang M, Xu HY, Wang YC, Shi ZB, Zhang NN. Structure of succinyl-CoA:3-ketoacid CoA transferase from Drosophila melanogaster. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Oct;69(Pt 10):1089-93., doi: 10.1107/S1744309113024986. Epub 2013 Sep 28. PMID:24100554 doi:http://dx.doi.org/10.1107/S1744309113024986

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OCA

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