2lna

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[[Image:2lna.png|left|200px]]
 
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{{STRUCTURE_2lna| PDB=2lna | SCENE= }}
{{STRUCTURE_2lna| PDB=2lna | SCENE= }}
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===Solution NMR Structure of the mitochondrial inner membrane domain (residues 164-251), FtsH_ext, from the paraplegin-like protein AFG3L2 from Homo sapiens, Northeast Structural Genomics Consortium Target HR6741A===
===Solution NMR Structure of the mitochondrial inner membrane domain (residues 164-251), FtsH_ext, from the paraplegin-like protein AFG3L2 from Homo sapiens, Northeast Structural Genomics Consortium Target HR6741A===
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{{ABSTRACT_PUBMED_24055473}}
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==Disease==
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[[http://www.uniprot.org/uniprot/AFG32_HUMAN AFG32_HUMAN]] Spinocerebellar ataxia type 28;Early-onset spastic ataxia-neuropathy syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
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==Function==
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[[http://www.uniprot.org/uniprot/AFG32_HUMAN AFG32_HUMAN]] ATP-dependent protease which is essential for axonal development (By similarity).
==About this Structure==
==About this Structure==
[[2lna]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LNA OCA].
[[2lna]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LNA OCA].
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==Reference==
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<ref group="xtra">PMID:024055473</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Acton, T B.]]
[[Category: Acton, T B.]]

Revision as of 08:18, 30 October 2013

Template:STRUCTURE 2lna

Contents

Solution NMR Structure of the mitochondrial inner membrane domain (residues 164-251), FtsH_ext, from the paraplegin-like protein AFG3L2 from Homo sapiens, Northeast Structural Genomics Consortium Target HR6741A

Template:ABSTRACT PUBMED 24055473

Disease

[AFG32_HUMAN] Spinocerebellar ataxia type 28;Early-onset spastic ataxia-neuropathy syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.

Function

[AFG32_HUMAN] ATP-dependent protease which is essential for axonal development (By similarity).

About this Structure

2lna is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Ramelot TA, Yang Y, Sahu ID, Lee HW, Xiao R, Lorigan GA, Montelione GT, Kennedy MA. NMR structure and MD simulations of the AAA protease intermembrane space domain indicates peripheral membrane localization within the hexaoligomer. FEBS Lett. 2013 Nov 1;587(21):3522-8. doi: 10.1016/j.febslet.2013.09.009. Epub, 2013 Sep 18. PMID:24055473 doi:http://dx.doi.org/10.1016/j.febslet.2013.09.009

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