4ek2

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[[Image:4ek2.jpg|left|200px]]
 
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{{STRUCTURE_4ek2| PDB=4ek2 | SCENE= }}
{{STRUCTURE_4ek2| PDB=4ek2 | SCENE= }}
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===The structure of nucleoside diphosphate kinase (NDK) from Burkholderia thailandensis bound to deoxyadenosine monophosphate===
===The structure of nucleoside diphosphate kinase (NDK) from Burkholderia thailandensis bound to deoxyadenosine monophosphate===
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{{ABSTRACT_PUBMED_23382856}}
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==Function==
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[[http://www.uniprot.org/uniprot/NDK_BURTA NDK_BURTA]] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).
==About this Structure==
==About this Structure==
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[[4ek2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_thailandensis Burkholderia thailandensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EK2 OCA].
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[[4ek2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_thailandensis_e264 Burkholderia thailandensis e264]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EK2 OCA].
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[[Category: Burkholderia thailandensis]]
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==Reference==
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<ref group="xtra">PMID:023382856</ref><references group="xtra"/><references/>
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[[Category: Burkholderia thailandensis e264]]
[[Category: Nucleoside-diphosphate kinase]]
[[Category: Nucleoside-diphosphate kinase]]
[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]

Revision as of 08:19, 30 October 2013

Template:STRUCTURE 4ek2

Contents

The structure of nucleoside diphosphate kinase (NDK) from Burkholderia thailandensis bound to deoxyadenosine monophosphate

Template:ABSTRACT PUBMED 23382856

Function

[NDK_BURTA] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).

About this Structure

4ek2 is a 2 chain structure with sequence from Burkholderia thailandensis e264. Full crystallographic information is available from OCA.

Reference

  • Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, Abendroth J, Fairman JW, Fox D 3rd, Staker BL, Phan I, Gillespie A, Choi R, Nakazawa-Hewitt S, Nguyen MT, Napuli A, Barrett L, Buchko GW, Stacy R, Myler PJ, Stewart LJ, Manoil C, Van Voorhis WC. Combining functional and structural genomics to sample the essential Burkholderia structome. PLoS One. 2013;8(1):e53851. doi: 10.1371/journal.pone.0053851. Epub 2013 Jan 31. PMID:23382856 doi:http://dx.doi.org/10.1371/journal.pone.0053851

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