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4kp0

From Proteopedia

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m (Protected "4kp0" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4kp0| PDB=4kp0 | SCENE= }}
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===Crystal Structure of the human Chymase with TJK002===
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{{ABSTRACT_PUBMED_24121339}}
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The entry 4kp0 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/CMA1_HUMAN CMA1_HUMAN]] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
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Authors: Kakuda, S., Takimoto-Kamimura, M.
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==About this Structure==
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[[4kp0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KP0 OCA].
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Description: Crystal Structure of the human Chymase with TJK002
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==Reference==
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<ref group="xtra">PMID:024121339</ref><references group="xtra"/><references/>
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[[Category: Chymase]]
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[[Category: Homo sapiens]]
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[[Category: Kakuda, S.]]
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[[Category: Takimoto-Kamimura, M.]]
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[[Category: Benzimidazole]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Protease]]
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[[Category: Serine protease]]

Revision as of 09:31, 30 October 2013

Template:STRUCTURE 4kp0

Contents

Crystal Structure of the human Chymase with TJK002

Template:ABSTRACT PUBMED 24121339

Function

[CMA1_HUMAN] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.

About this Structure

4kp0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Matsumoto Y, Kakuda S, Koizumi M, Mizuno T, Muroga Y, Kawamura T, Takimoto-Kamimura M. Crystal structure of a complex of human chymase with its benzimidazole derived inhibitor. J Synchrotron Radiat. 2013 Nov;20(Pt 6):914-8. doi: 10.1107/S0909049513020748., Epub 2013 Sep 25. PMID:24121339 doi:http://dx.doi.org/10.1107/S0909049513020748

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OCA

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