4lpb

(Difference between revisions)

Revision as of 09:33, 30 October 2013

4lpb is a 1 chain structure with sequence from Streptococcus pneumoniae r6. Full crystallographic information is available from OCA.

Basarab GS, Manchester JI, Bist S, Boriack-Sjodin PA, Dangel B, Illingworth R, Sherer BA, Sriram S, Uria-Nickelsen M, Eakin AE. Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents. J Med Chem. 2013 Oct 29. PMID:24098982 doi:http://dx.doi.org/10.1021/jm401208b

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-'''Unreleased structure'''
+{{STRUCTURE_4lpb|  PDB=4lpb  |  SCENE=  }}
+===Crystal structure of a topoisomerase ATPase inhibitor===
+{{ABSTRACT_PUBMED_24098982}}
-The entry 4lpb is ON HOLD  until Paper Publication
+==About this Structure==
+[[4lpb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_r6 Streptococcus pneumoniae r6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LPB OCA].
-Authors: Boriack-Sjodin, A.
+==Reference==
+<ref group="xtra">PMID:024098982</ref><references group="xtra"/><references/>
-Description: Crystal structure of a topoisomerase ATPase inhibitor
+[[Category: Streptococcus pneumoniae r6]]
+[[Category: Boriack-Sjodin, A.]]
+[[Category: Antimicrobial]]
+[[Category: Atp binding]]
+[[Category: Atp binding domain]]
+[[Category: Isomerase-isomerase inhibitor complex]]
+[[Category: Protein-inhibitor complex]]
+[[Category: Structure-based drug design]]
+[[Category: Virtual screen]]