4ljh

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'''Unreleased structure'''
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{{STRUCTURE_4ljh| PDB=4ljh | SCENE= }}
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===Crystal Structure of Pseudomonas aeruginosa Lectin LecA Complexed with 1-Methyl-3-indolyl-b-D-galactopyranoside at 1.45 A Resolution===
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{{ABSTRACT_PUBMED_23869965}}
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The entry 4ljh is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE]] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.
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Authors: Kadam, R.U., Stocker, A., Reymond, J.-L.
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==About this Structure==
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[[4ljh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LJH OCA].
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Description: Crystal Structure of Pseudomonas aeruginosa Lectin LecA Complexed with 1-Methyl-3-indolyl-b-D-galactopyranoside at 1.45 A Resolution
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==Reference==
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<ref group="xtra">PMID:023869965</ref><references group="xtra"/><references/>
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[[Category: Pseudomonas aeruginosa pao1]]
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[[Category: Kadam, R U.]]
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[[Category: Reymond, J L.]]
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[[Category: Stocker, A.]]
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[[Category: Adhesin]]
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[[Category: Galactose]]
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[[Category: Galactose-specific]]
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[[Category: Galactoside]]
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[[Category: Glycosphingolipid-antigen]]
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[[Category: Glycosylation]]
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[[Category: Lectin fold]]
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[[Category: Outer membrane]]
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[[Category: Sugar binding protein]]

Revision as of 09:35, 30 October 2013

Template:STRUCTURE 4ljh

Contents

Crystal Structure of Pseudomonas aeruginosa Lectin LecA Complexed with 1-Methyl-3-indolyl-b-D-galactopyranoside at 1.45 A Resolution

Template:ABSTRACT PUBMED 23869965

Function

[PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.

About this Structure

4ljh is a 4 chain structure with sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.

Reference

  • Kadam RU, Garg D, Schwartz J, Visini R, Sattler M, Stocker A, Darbre T, Reymond JL. CH-pi "T-Shape" Interaction with Histidine Explains Binding of Aromatic Galactosides to Pseudomonas aeruginosa Lectin LecA. ACS Chem Biol. 2013 Sep 20;8(9):1925-30. doi: 10.1021/cb400303w. Epub 2013 Jul, 31. PMID:23869965 doi:http://dx.doi.org/10.1021/cb400303w

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OCA

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