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4bkk

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4bkk| PDB=4bkk | SCENE= }}
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===The Respiratory Syncytial Virus nucleoprotein-RNA complex forms a left-handed helical nucleocapsid.===
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{{ABSTRACT_PUBMED_23677789}}
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The entry 4bkk is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/NCAP_HRSVA NCAP_HRSVA]] Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.<ref>PMID:9299631</ref>
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Authors: Bakker, S.E., Duquerroy, S., Galloux, M., Loney, C., Conner, E., Eleouet, J.F., Rey, F.A., Bhella, D.
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==About this Structure==
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[[4bkk]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_respiratory_syncytial_virus_a_strain_long Human respiratory syncytial virus a strain long]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BKK OCA].
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Description: The Respiratory Syncytial Virus nucleoprotein-RNA complex forms a left-handed helical nucleocapsid.
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==Reference==
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<ref group="xtra">PMID:023677789</ref><references group="xtra"/><references/>
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[[Category: Human respiratory syncytial virus a strain long]]
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[[Category: Bakker, S E.]]
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[[Category: Bhella, D.]]
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[[Category: Conner, E.]]
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[[Category: Duquerroy, S.]]
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[[Category: Eleouet, J F.]]
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[[Category: Galloux, M.]]
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[[Category: Loney, C.]]
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[[Category: Rey, F A.]]
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[[Category: Viral protein-rna complex]]

Revision as of 09:40, 30 October 2013

Template:STRUCTURE 4bkk

Contents

The Respiratory Syncytial Virus nucleoprotein-RNA complex forms a left-handed helical nucleocapsid.

Template:ABSTRACT PUBMED 23677789

Function

[NCAP_HRSVA] Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.[1]

About this Structure

4bkk is a 24 chain structure with sequence from Human respiratory syncytial virus a strain long. Full crystallographic information is available from OCA.

Reference

  • Bakker SE, Duquerroy S, Galloux M, Loney C, Conner E, Eleouet JF, Rey FA, Bhella D. The respiratory syncytial virus nucleoprotein-RNA complex forms a left-handed helical nucleocapsid. J Gen Virol. 2013 Aug;94(Pt 8):1734-8. doi: 10.1099/vir.0.053025-0. Epub 2013 May, 15. PMID:23677789 doi:http://dx.doi.org/10.1099/vir.0.053025-0
  1. ↑ Fearns R, Peeples ME, Collins PL. Increased expression of the N protein of respiratory syncytial virus stimulates minigenome replication but does not alter the balance between the synthesis of mRNA and antigenome. Virology. 1997 Sep 15;236(1):188-201. PMID:9299631 doi:10.1006/viro.1997.8734

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