4cc2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "4cc2" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4cc2| PDB=4cc2 | SCENE= }}
 +
===Complex of human Tuba C-terminal SH3 domain with human N-WASP proline- rich peptide - P212121===
-
The entry 4cc2 is ON HOLD
+
==Function==
 +
[[http://www.uniprot.org/uniprot/DNMBP_HUMAN DNMBP_HUMAN]] Scaffold protein that links dynamin with actin-regulating proteins. May play a role in membrane trafficking between the cell surface and the Golgi (By similarity). [[http://www.uniprot.org/uniprot/WASL_HUMAN WASL_HUMAN]] Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression.<ref>PMID:19366662</ref>
-
Authors: Polle, L., Rigano, L., Julian, R., Ireton, K., Schubert, W.-D.
+
==About this Structure==
 +
[[4cc2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CC2 OCA].
-
Description: Complex of human Tuba C-terminal SH3 domain with human N-WASP proline-rich peptide -P212121
+
==Reference==
 +
<references group="xtra"/><references/>
 +
[[Category: Homo sapiens]]
 +
[[Category: Ireton, K.]]
 +
[[Category: Julian, R.]]
 +
[[Category: Polle, L.]]
 +
[[Category: Rigano, L.]]
 +
[[Category: Schubert, W D.]]
 +
[[Category: Actin cytoskeleton]]
 +
[[Category: Cortical tension]]
 +
[[Category: Proline-rich peptide]]
 +
[[Category: Sh3 domain]]
 +
[[Category: Src homology 3]]
 +
[[Category: Structural protein]]

Revision as of 09:48, 30 October 2013

Template:STRUCTURE 4cc2

Contents

Complex of human Tuba C-terminal SH3 domain with human N-WASP proline- rich peptide - P212121

Function

[DNMBP_HUMAN] Scaffold protein that links dynamin with actin-regulating proteins. May play a role in membrane trafficking between the cell surface and the Golgi (By similarity). [WASL_HUMAN] Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression.[1]

About this Structure

4cc2 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. ↑ Vingadassalom D, Kazlauskas A, Skehan B, Cheng HC, Magoun L, Robbins D, Rosen MK, Saksela K, Leong JM. Insulin receptor tyrosine kinase substrate links the E. coli O157:H7 actin assembly effectors Tir and EspF(U) during pedestal formation. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6754-9. doi:, 10.1073/pnas.0809131106. Epub 2009 Apr 6. PMID:19366662 doi:10.1073/pnas.0809131106

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4cc2"
Personal tools