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Ku protein
From Proteopedia
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== Ku Ring == | == Ku Ring == | ||
<scene name='56/567269/Ku_ring/1'>Ku Ring</scene> | <scene name='56/567269/Ku_ring/1'>Ku Ring</scene> | ||
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| + | Instead of most DNA binding proteins, the Ku heterodimer contains a ring that encircles the DNA helix, with preference towards DNA ends. By binding to the DNA end, the Ku ring protects the broken DNA strands from degradation and from base pairing to another DNA strand. | ||
Revision as of 17:44, 3 November 2013
Structure of the Ku heterodimer bound to DNA
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References
- ↑ Walker JR, Corpina RA, Goldberg J. Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair. Nature. 2001 Aug 9;412(6847):607-14. PMID:11493912 doi:10.1038/35088000
