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1vvk

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{{STRUCTURE_1vvk| PDB=1vvk | SCENE= }}
{{STRUCTURE_1vvk| PDB=1vvk | SCENE= }}
===Structure of the Methanococcus jannaschii ribosome-SecYEBeta channel complex (SecYEBeta + 50S ribosomal proteins)===
===Structure of the Methanococcus jannaschii ribosome-SecYEBeta channel complex (SecYEBeta + 50S ribosomal proteins)===
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{{ABSTRACT_PUBMED_24153188}}
==Function==
==Function==
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==About this Structure==
==About this Structure==
[[1vvk]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VVK OCA].
[[1vvk]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VVK OCA].
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==Reference==
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<ref group="xtra">PMID:024153188</ref><references group="xtra"/><references/>
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Akey, C W.]]
[[Category: Akey, C W.]]

Revision as of 05:50, 6 November 2013

Template:STRUCTURE 1vvk

Contents

Structure of the Methanococcus jannaschii ribosome-SecYEBeta channel complex (SecYEBeta + 50S ribosomal proteins)

Template:ABSTRACT PUBMED 24153188

Function

[SECY_METJA] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. [SECG_METJA] Subunit of the protein translocation channel SecYEG. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. [SECE_METJA] Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

About this Structure

1vvk is a 9 chain structure with sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA.

Reference

  • Park E, Menetret JF, Gumbart JC, Ludtke SJ, Li W, Whynot A, Rapoport TA, Akey CW. Structure of the SecY channel during initiation of protein translocation. Nature. 2013 Oct 23. doi: 10.1038/nature12720. PMID:24153188 doi:http://dx.doi.org/10.1038/nature12720

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