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1fmc
From Proteopedia
(Difference between revisions)
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===7-ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEX WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID=== | ===7-ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEX WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID=== | ||
{{ABSTRACT_PUBMED_8672472}} | {{ABSTRACT_PUBMED_8672472}} | ||
| + | |||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/HDHA_ECOLI HDHA_ECOLI]] 7-alpha-dehydroxylation of cholic acid, yielding deoxycholic acid and lithocholic acid, respectively. Highest affinity with taurochenodeoxycholic acid. | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:008672472</ref><references group="xtra"/> | + | <ref group="xtra">PMID:008672472</ref><references group="xtra"/><references/> |
[[Category: 7-alpha-hydroxysteroid dehydrogenase]] | [[Category: 7-alpha-hydroxysteroid dehydrogenase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
Revision as of 05:57, 6 November 2013
Contents |
7-ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEX WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID
Template:ABSTRACT PUBMED 8672472
Function
[HDHA_ECOLI] 7-alpha-dehydroxylation of cholic acid, yielding deoxycholic acid and lithocholic acid, respectively. Highest affinity with taurochenodeoxycholic acid.
About this Structure
1fmc is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
See Also
Reference
- Tanaka N, Nonaka T, Tanabe T, Yoshimoto T, Tsuru D, Mitsui Y. Crystal structures of the binary and ternary complexes of 7 alpha-hydroxysteroid dehydrogenase from Escherichia coli. Biochemistry. 1996 Jun 18;35(24):7715-30. PMID:8672472 doi:10.1021/bi951904d
