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1fmc

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===7-ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEX WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID===
===7-ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEX WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID===
{{ABSTRACT_PUBMED_8672472}}
{{ABSTRACT_PUBMED_8672472}}
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==Function==
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[[http://www.uniprot.org/uniprot/HDHA_ECOLI HDHA_ECOLI]] 7-alpha-dehydroxylation of cholic acid, yielding deoxycholic acid and lithocholic acid, respectively. Highest affinity with taurochenodeoxycholic acid.
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:008672472</ref><references group="xtra"/>
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<ref group="xtra">PMID:008672472</ref><references group="xtra"/><references/>
[[Category: 7-alpha-hydroxysteroid dehydrogenase]]
[[Category: 7-alpha-hydroxysteroid dehydrogenase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]

Revision as of 05:57, 6 November 2013

Template:STRUCTURE 1fmc

Contents

7-ALPHA-HYDROXYSTEROID DEHYDROGENASE COMPLEX WITH NADH AND 7-OXO GLYCOCHENODEOXYCHOLIC ACID

Template:ABSTRACT PUBMED 8672472

Function

[HDHA_ECOLI] 7-alpha-dehydroxylation of cholic acid, yielding deoxycholic acid and lithocholic acid, respectively. Highest affinity with taurochenodeoxycholic acid.

About this Structure

1fmc is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  • Tanaka N, Nonaka T, Tanabe T, Yoshimoto T, Tsuru D, Mitsui Y. Crystal structures of the binary and ternary complexes of 7 alpha-hydroxysteroid dehydrogenase from Escherichia coli. Biochemistry. 1996 Jun 18;35(24):7715-30. PMID:8672472 doi:10.1021/bi951904d

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