4g09
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4g09| PDB=4g09 | SCENE= }} | {{STRUCTURE_4g09| PDB=4g09 | SCENE= }} | ||
===The crystal structure of the C366S mutant of HDH from Brucella suis in complex with a substituted benzyl ketone=== | ===The crystal structure of the C366S mutant of HDH from Brucella suis in complex with a substituted benzyl ketone=== | ||
| + | {{ABSTRACT_PUBMED_24140957}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4g09]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Brucella_suis_1330 Brucella suis 1330]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G09 OCA]. | [[4g09]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Brucella_suis_1330 Brucella suis 1330]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G09 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:024140957</ref><references group="xtra"/><references/> | ||
[[Category: Brucella suis 1330]] | [[Category: Brucella suis 1330]] | ||
[[Category: Histidinol dehydrogenase]] | [[Category: Histidinol dehydrogenase]] | ||
Revision as of 06:19, 6 November 2013
Contents |
The crystal structure of the C366S mutant of HDH from Brucella suis in complex with a substituted benzyl ketone
Template:ABSTRACT PUBMED 24140957
Function
[HISX_BRUSU] Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine (By similarity).
About this Structure
4g09 is a 1 chain structure with sequence from Brucella suis 1330. Full crystallographic information is available from OCA.
Reference
- D'ambrosio K, Lopez M, Dathan NA, Ouahrani-Bettache S, Kohler S, Ascione G, Monti SM, Winum JY, De Simone G. Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis. Biochimie. 2013 Oct 17. pii: S0300-9084(13)00349-0. doi:, 10.1016/j.biochi.2013.09.028. PMID:24140957 doi:http://dx.doi.org/10.1016/j.biochi.2013.09.028
