4cbf

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m (Protected "4cbf" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4cbf| PDB=4cbf | SCENE= }}
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===Near-atomic resolution cryo-EM structure of Dengue serotype 4 virus===
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{{ABSTRACT_PUBMED_24155405}}
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The entry 4cbf is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/E0WXI2_9FLAV E0WXI2_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS011998_004_099774]
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Authors: Kostyuchenko, V.A., Chew, P.L., Ng, T.S., Lok, S.M.
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==About this Structure==
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[[4cbf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_2 Dengue virus 2] and [http://en.wikipedia.org/wiki/Dengue_virus_4 Dengue virus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CBF OCA].
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Description: Near-atomic resolution cryo-EM structure of Dengue serotype 4 virus
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==Reference==
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<ref group="xtra">PMID:024155405</ref><references group="xtra"/><references/>
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[[Category: Dengue virus 2]]
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[[Category: Dengue virus 4]]
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[[Category: Chew, P L.]]
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[[Category: Kostyuchenko, V A.]]
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[[Category: Lok, S M.]]
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[[Category: Ng, T S.]]
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[[Category: Flavivirus]]
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[[Category: Virus]]

Revision as of 07:39, 6 November 2013

Template:STRUCTURE 4cbf

Contents

Near-atomic resolution cryo-EM structure of Dengue serotype 4 virus

Template:ABSTRACT PUBMED 24155405

Function

[E0WXI2_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS011998_004_099774]

About this Structure

4cbf is a 6 chain structure with sequence from Dengue virus 2 and Dengue virus 4. Full crystallographic information is available from OCA.

Reference

Proteopedia Page Contributors and Editors (what is this?)

OCA

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