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4g33

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'''Unreleased structure'''
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{{STRUCTURE_4g33| PDB=4g33 | SCENE= }}
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===Crystal Structure of a Phospholipid-Lipoxygenase Complex from Pseudomonas aeruginosa at 2.0 A (C2221)===
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{{ABSTRACT_PUBMED_23985801}}
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The entry 4g33 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/LOX_PSEAI LOX_PSEAI]] In presence of oxygen, converts oleic acid into (S)-(E)-10-hydroperoxy-8-octadecenoic acid (HPOD), which spontaneously decomposes to the corresponding (E)-10-hydroxy-8-octadecenoic acid (HOD). In vivo, the reaction leads to the dihydroxy derivative (E)-7,10-dihydroxy-8-octadecenoic acid (DHOD), so that the three hydroxy-fatty acids can be isolated from the culture medium. Also active on linoleic acid and linolenic acid. Almost not active on arachidonic acid.
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Authors: Carpena, X., Garreta, A., Val-Moraes, S.P., Garcia-Fernandez, Q., Fita, I.
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==About this Structure==
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[[4g33]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G33 OCA].
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Description: Crystal Structure of a Phospholipid-Lipoxygenase Complex from Pseudomonas aeruginosa at 2.0 A (C2221)
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==Reference==
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<ref group="xtra">PMID:023985801</ref><references group="xtra"/><references/>
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Carpena, X.]]
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[[Category: Fita, I.]]
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[[Category: Garcia-Fernandez, Q.]]
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[[Category: Garreta, A.]]
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[[Category: Val-Moraes, S P.]]
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[[Category: Non-heme iron enzyme]]
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[[Category: Oxidoreductase]]
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[[Category: Protein-phospholipid complex]]

Revision as of 07:39, 6 November 2013

Template:STRUCTURE 4g33

Contents

Crystal Structure of a Phospholipid-Lipoxygenase Complex from Pseudomonas aeruginosa at 2.0 A (C2221)

Template:ABSTRACT PUBMED 23985801

Function

[LOX_PSEAI] In presence of oxygen, converts oleic acid into (S)-(E)-10-hydroperoxy-8-octadecenoic acid (HPOD), which spontaneously decomposes to the corresponding (E)-10-hydroxy-8-octadecenoic acid (HOD). In vivo, the reaction leads to the dihydroxy derivative (E)-7,10-dihydroxy-8-octadecenoic acid (DHOD), so that the three hydroxy-fatty acids can be isolated from the culture medium. Also active on linoleic acid and linolenic acid. Almost not active on arachidonic acid.

About this Structure

4g33 is a 1 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

  • Garreta A, Val-Moraes SP, Garcia-Fernandez Q, Busquets M, Juan C, Oliver A, Ortiz A, Gaffney BJ, Fita I, Manresa A, Carpena X. Structure and interaction with phospholipids of a prokaryotic lipoxygenase from Pseudomonas aeruginosa. FASEB J. 2013 Aug 30. PMID:23985801 doi:http://dx.doi.org/10.1096/fj.13-235952

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OCA

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