4ige

(Difference between revisions)

Revision as of 07:41, 6 November 2013

4ige is a 2 chain structure with sequence from Plasmodium falciparum 3d7. Full crystallographic information is available from OCA.

Belluti F, Perozzo R, Lauciello L, Colizzi F, Kostrewa D, Bisi A, Gobbi S, Rampa A, Bolognesi ML, Recanatini M, Brun R, Scapozza L, Cavalli A. Design, Synthesis, and Biological and Crystallographic Evaluation of Novel Inhibitors of Plasmodium falciparum Enoyl-ACP-reductase (PfFabI). J Med Chem. 2013 Oct 10;56(19):7516-26. doi: 10.1021/jm400637m. Epub 2013 Sep 25. PMID:24063369 doi:http://dx.doi.org/10.1021/jm400637m

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-'''Unreleased structure'''
+{{STRUCTURE_4ige|  PDB=4ige  |  SCENE=  }}
+===Crystal structure of Plasmodium falciparum FabI complexed with NAD and inhibitor 7-(4-Chloro-2-hydroxyphenoxy)-4-methyl-2H-chromen-2-one===
+{{ABSTRACT_PUBMED_24063369}}
-The entry 4ige is ON HOLD  until Paper Publication
+==About this Structure==
+[[4ige]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IGE OCA].
-Authors: Kostrewa, D., Perozzo, R.
+==Reference==
+<ref group="xtra">PMID:024063369</ref><references group="xtra"/><references/>
-Description: Crystal structure of Plasmodium falciparum FabI complexed with NAD and inhibitor 7-(4-Chloro-2-hydroxyphenoxy)-4-methyl-2H-chromen-2-one
+[[Category: Plasmodium falciparum 3d7]]
+[[Category: Kostrewa, D.]]
+[[Category: Perozzo, R.]]
+[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+[[Category: Reductase]]