4imf

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'''Unreleased structure'''
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{{STRUCTURE_4imf| PDB=4imf | SCENE= }}
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===Crystal Structure of Pasteurella multocida N-Acetyl-D-Neuraminic acid lyase K164 mutant complexed with N-Acetylneuraminic acid===
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{{ABSTRACT_PUBMED_24152047}}
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The entry 4imf is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/NANA_PASMU NANA_PASMU]] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate (By similarity).
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Authors: Fisher, A.J., Huynh, N.
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==About this Structure==
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[[4imf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pasteurella_multocida_subsp._gallicida_p1059 Pasteurella multocida subsp. gallicida p1059]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IMF OCA].
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Description: Crystal Structure of Pasteurella multocida N-Acetyl-D-Neuraminic acid lyase K164 mutant complexed with N-Acetylneuraminic acid
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==Reference==
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<ref group="xtra">PMID:024152047</ref><references group="xtra"/><references/>
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[[Category: N-acetylneuraminate lyase]]
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[[Category: Pasteurella multocida subsp. gallicida p1059]]
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[[Category: Fisher, A J.]]
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[[Category: Huynh, N.]]
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[[Category: Lyase]]
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[[Category: Schiff base]]
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[[Category: Tim barrel]]

Revision as of 07:42, 6 November 2013

Template:STRUCTURE 4imf

Contents

Crystal Structure of Pasteurella multocida N-Acetyl-D-Neuraminic acid lyase K164 mutant complexed with N-Acetylneuraminic acid

Template:ABSTRACT PUBMED 24152047

Function

[NANA_PASMU] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate (By similarity).

About this Structure

4imf is a 2 chain structure with sequence from Pasteurella multocida subsp. gallicida p1059. Full crystallographic information is available from OCA.

Reference

  • Huynh N, Aye A, Li Y, Yu H, Cao H, Tiwari VK, Shin DW, Chen X, Fisher AJ. Structural basis for substrate specificity and mechanism of N-acetyl-D-neuraminic acid lyase from Pasteurella multocida. Biochemistry. 2013 Oct 23. PMID:24152047 doi:http://dx.doi.org/10.1021/bi4011754

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OCA

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