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4blv
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[4blv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[4blv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BLV OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:023945937</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:023945937</ref><references group="xtra"/><references/> | ||
| - | [[Category: | + | [[Category: Ecoli]] |
[[Category: Forster, A C.]] | [[Category: Forster, A C.]] | ||
[[Category: Liljeruhm, J.]] | [[Category: Liljeruhm, J.]] | ||
Revision as of 06:31, 13 November 2013
Contents |
Crystal structure of Escherichia coli 23S rRNA (A2030-N6)- methyltransferase RlmJ in complex with S-adenosylmethionine (AdoMet)
Template:ABSTRACT PUBMED 23945937
Function
[RLMJ_ECOLI] Specifically methylates the adenine in position 2030 of 23S rRNA. Nascent 23S rRNA seems to be the natural substrate. Appears to be not necessary for ribosome assembly. Seems to be required for the utilization of extracellular DNA as the sole source of carbon and energy.[1] [2]
About this Structure
4blv is a 2 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.
Reference
- Punekar AS, Liljeruhm J, Shepherd TR, Forster AC, Selmer M. Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ. Nucleic Acids Res. 2013 Aug 13. PMID:23945937 doi:10.1093/nar/gkt719
- ↑ Palchevskiy V, Finkel SE. Escherichia coli competence gene homologs are essential for competitive fitness and the use of DNA as a nutrient. J Bacteriol. 2006 Jun;188(11):3902-10. PMID:16707682 doi:10.1128/JB.01974-05
- ↑ Golovina AY, Dzama MM, Osterman IA, Sergiev PV, Serebryakova MV, Bogdanov AA, Dontsova OA. The last rRNA methyltransferase of E. coli revealed: the yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA. RNA. 2012 Sep;18(9):1725-34. doi: 10.1261/rna.034207.112. Epub 2012 Jul 30. PMID:22847818 doi:10.1261/rna.034207.112
