4m1m
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4m1m| PDB=4m1m | SCENE= }} | |
| + | ===Corrected Structure of Mouse P-glycoprotein=== | ||
| + | {{ABSTRACT_PUBMED_24155053}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref> | ||
| - | + | ==About this Structure== | |
| + | [[4m1m]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M1M OCA]. | ||
| - | + | ==Reference== | |
| + | <ref group="xtra">PMID:024155053</ref><references group="xtra"/><references/> | ||
| + | [[Category: Xenobiotic-transporting ATPase]] | ||
| + | [[Category: Aller, S G.]] | ||
| + | [[Category: Jaimes, K F.]] | ||
| + | [[Category: Li, J.]] | ||
| + | [[Category: Adenosine triphosphate]] | ||
| + | [[Category: Atp-binding cassette transporter]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Mercurated cysteine]] | ||
| + | [[Category: Multidrug efflux]] | ||
| + | [[Category: Plasma membrane]] | ||
Revision as of 08:15, 13 November 2013
Contents |
Corrected Structure of Mouse P-glycoprotein
Template:ABSTRACT PUBMED 24155053
Function
[MDR1A_MOUSE] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.[1]
About this Structure
4m1m is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Li J, Jaimes KF, Aller SG. Refined structures of mouse P-Glycoprotein. Protein Sci. 2013 Oct 24. doi: 10.1002/pro.2387. PMID:24155053 doi:http://dx.doi.org/10.1002/pro.2387
- ↑ Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, Harrell PM, Trinh YT, Zhang Q, Urbatsch IL, Chang G. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science. 2009 Mar 27;323(5922):1718-22. PMID:19325113 doi:323/5922/1718
