4lp0

(Difference between revisions)

Revision as of 08:19, 13 November 2013

4lp0 is a 1 chain structure. Full crystallographic information is available from OCA.

Basarab GS, Manchester JI, Bist S, Boriack-Sjodin PA, Dangel B, Illingworth R, Sherer BA, Sriram S, Uria-Nickelsen M, Eakin AE. Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents. J Med Chem. 2013 Oct 29. PMID:24098982 doi:http://dx.doi.org/10.1021/jm401208b

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-'''Unreleased structure'''
+{{STRUCTURE_4lp0|  PDB=4lp0  |  SCENE=  }}
+===Crystal structure of a topoisomerase ATP inhibitor===
+{{ABSTRACT_PUBMED_24098982}}
-The entry 4lp0 is ON HOLD  until sometime in the future
+==About this Structure==
+[[4lp0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LP0 OCA].
-Authors: Basarab, G.S., Manchester, J.I., Bist, S., Boriack-Sjodin, P.A., Dangel, B., Illingsworth, R., Uria-Nickelsen, M., Sherer, B.A., Sriram, S., Eakin, A.E.
+==Reference==
+<ref group="xtra">PMID:024098982</ref><references group="xtra"/><references/>
-Description: Crystal structure of a topoisomerase ATP inhibitor
+[[Category: Basarab, G S.]]
+[[Category: Bist, S.]]
+[[Category: Boriack-Sjodin, P A.]]
+[[Category: Dangel, B.]]
+[[Category: Eakin, A E.]]
+[[Category: Illingsworth, R.]]
+[[Category: Manchester, J I.]]
+[[Category: Sherer, B A.]]
+[[Category: Sriram, S.]]
+[[Category: Uria-Nickelsen, M.]]
+[[Category: Antimicrobial]]
+[[Category: Atp binding]]
+[[Category: Atpase domain]]
+[[Category: Isomerase-isomerase inhibitor complex]]
+[[Category: Protein-inhibitor complex]]
+[[Category: Structure-based drug design]]
+[[Category: Virtual screen]]