4n7q

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4n7q| PDB=4n7q | SCENE= }}
 +
===Crystal structure of eukaryotic THIC from A. thaliana===
 +
{{ABSTRACT_PUBMED_24161603}}
-
The entry 4n7q is ON HOLD until Paper Publication
+
==Function==
 +
[[http://www.uniprot.org/uniprot/THIC_ARATH THIC_ARATH]] Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<ref>PMID:18048325</ref> <ref>PMID:18332905</ref>
-
Authors: Coquille, S.C., Roux, C., Mehta, A., Begley, T.P., Fitzpatrick, T.B., Thore, S.
+
==About this Structure==
 +
[[4n7q]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N7Q OCA].
-
Description: Crystal structure of eukaryotic THIC from A. thaliana
+
==Reference==
 +
<ref group="xtra">PMID:024161603</ref><references group="xtra"/><references/>
 +
[[Category: Phosphomethylpyrimidine synthase]]
 +
[[Category: Begley, T P.]]
 +
[[Category: Coquille, S C.]]
 +
[[Category: Fitzpatrick, T B.]]
 +
[[Category: Mehta, A.]]
 +
[[Category: Roux, C.]]
 +
[[Category: Thore, S.]]
 +
[[Category: Hmp-p synthase]]
 +
[[Category: Lyase]]
 +
[[Category: Metal binding site]]
 +
[[Category: Sam radical dependent enzyme]]

Revision as of 08:20, 13 November 2013

Template:STRUCTURE 4n7q

Contents

Crystal structure of eukaryotic THIC from A. thaliana

Template:ABSTRACT PUBMED 24161603

Function

[THIC_ARATH] Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.[1] [2]

About this Structure

4n7q is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Coquille S, Roux C, Mehta A, Begley TP, Fitzpatrick TB, Thore S. High-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thaliana. J Struct Biol. 2013 Oct 23. pii: S1047-8477(13)00270-0. doi:, 10.1016/j.jsb.2013.10.005. PMID:24161603 doi:http://dx.doi.org/10.1016/j.jsb.2013.10.005
  1. ↑ Raschke M, Burkle L, Muller N, Nunes-Nesi A, Fernie AR, Arigoni D, Amrhein N, Fitzpatrick TB. Vitamin B1 biosynthesis in plants requires the essential iron sulfur cluster protein, THIC. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19637-42. Epub 2007 Nov 28. PMID:18048325 doi:http://dx.doi.org/10.1073/pnas.0709597104
  2. ↑ Kong D, Zhu Y, Wu H, Cheng X, Liang H, Ling HQ. AtTHIC, a gene involved in thiamine biosynthesis in Arabidopsis thaliana. Cell Res. 2008 May;18(5):566-76. doi: 10.1038/cr.2008.35. PMID:18332905 doi:http://dx.doi.org/10.1038/cr.2008.35

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4n7q"
Personal tools