4kop

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'''Unreleased structure'''
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{{STRUCTURE_4kop| PDB=4kop | SCENE= }}
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===Crystal Structure of WHY2 from Arabidopsis thaliana===
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The entry 4kop is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/WHY2_ARATH WHY2_ARATH]] Single-stranded DNA-binding protein that associates with mitochondrial DNA and may play a role in the regulation of the gene expression machinery. Seems also to be required to prevent break-induced DNA rearrangements in the mitochondrial genome. Can bind to melt double-stranded DNA in vivo.<ref>PMID:18423020</ref> <ref>PMID:20551348</ref> <ref>PMID:22762281</ref>
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Authors: Cappadocia, L., Parent, J.S., Brisson, N., Sygusch, J.
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==About this Structure==
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[[4kop]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KOP OCA].
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Description: Crystal Structure of WHY2 from Arabidopsis thaliana
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Brisson, N.]]
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[[Category: Cappadocia, L.]]
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[[Category: Parent, J S.]]
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[[Category: Sygusch, J.]]
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[[Category: Dna binding protein]]
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[[Category: Plant]]
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[[Category: Whirly]]

Revision as of 08:29, 13 November 2013

Template:STRUCTURE 4kop

Contents

Crystal Structure of WHY2 from Arabidopsis thaliana

Function

[WHY2_ARATH] Single-stranded DNA-binding protein that associates with mitochondrial DNA and may play a role in the regulation of the gene expression machinery. Seems also to be required to prevent break-induced DNA rearrangements in the mitochondrial genome. Can bind to melt double-stranded DNA in vivo.[1] [2] [3]

About this Structure

4kop is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Marechal A, Parent JS, Sabar M, Veronneau-Lafortune F, Abou-Rached C, Brisson N. Overexpression of mtDNA-associated AtWhy2 compromises mitochondrial function. BMC Plant Biol. 2008 Apr 18;8:42. doi: 10.1186/1471-2229-8-42. PMID:18423020 doi:http://dx.doi.org/10.1186/1471-2229-8-42
  2. ↑ Cappadocia L, Marechal A, Parent JS, Lepage E, Sygusch J, Brisson N. Crystal structures of DNA-Whirly complexes and their role in Arabidopsis organelle genome repair. Plant Cell. 2010 Jun;22(6):1849-67. Epub 2010 Jun 15. PMID:20551348 doi:10.1105/tpc.109.071399
  3. ↑ Janicka S, Kuhn K, Le Ret M, Bonnard G, Imbault P, Augustyniak H, Gualberto JM. A RAD52-like single-stranded DNA binding protein affects mitochondrial DNA repair by recombination. Plant J. 2012 Nov;72(3):423-35. doi: 10.1111/j.1365-313X.2012.05097.x. Epub 2012 , Aug 30. PMID:22762281 doi:http://dx.doi.org/10.1111/j.1365-313X.2012.05097.x

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