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4lf3
From Proteopedia
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| - | + | {{STRUCTURE_4lf3| PDB=4lf3 | SCENE= }} | |
| + | ===Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor=== | ||
| - | The | + | ==Function== |
| + | [[http://www.uniprot.org/uniprot/GLR_HUMAN GLR_HUMAN]] This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. | ||
| - | + | ==About this Structure== | |
| - | + | [[4lf3]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LF3 OCA]. | |
| - | + | [[Category: Mukund, S.]] | |
| + | [[Category: Murray, J M.]] | ||
| + | [[Category: Fab fragment]] | ||
| + | [[Category: Gcgr]] | ||
| + | [[Category: Immune system]] | ||
Revision as of 08:29, 13 November 2013
Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor
Function
[GLR_HUMAN] This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
About this Structure
4lf3 is a 6 chain structure. Full crystallographic information is available from OCA.
