4lux
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
| - | [[4lux]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[4lux]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUX OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024145412</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024145412</ref><references group="xtra"/><references/> | ||
| - | [[Category: | + | [[Category: Buffalo rat]] |
[[Category: Li, H.]] | [[Category: Li, H.]] | ||
[[Category: Poulos, T L.]] | [[Category: Poulos, T L.]] | ||
[[Category: Nitric oxide synthase]] | [[Category: Nitric oxide synthase]] | ||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
Revision as of 12:19, 20 November 2013
Contents |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-((((3R,5S)-5-(((6-amino-4-methylpyridin-2-yl)methoxy)methyl)pyrrolidin-3-yl)oxy)methyl)-4-methylpyridin-2-amine
Template:ABSTRACT PUBMED 24145412
Function
[NOS1_RAT] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. Inhibitory transmitter for non-adrenergic and non-cholinergic nerves in the colorectum.
About this Structure
4lux is a 2 chain structure with sequence from Buffalo rat. Full crystallographic information is available from OCA.
Reference
- Holden JK, Li H, Jing Q, Kang S, Richo J, Silverman RB, Poulos TL. Structural and biological studies on bacterial nitric oxide synthase inhibitors. Proc Natl Acad Sci U S A. 2013 Oct 21. PMID:24145412 doi:http://dx.doi.org/10.1073/pnas.1314080110
