Metabotropic glutamate receptor

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Revision as of 19:07, 21 November 2013

Metabotropic glutamate receptors are glutamate receptors that -... They are members of the large class of seven-transmembrane domain receptors, the G protein-coupled receptors.

spinqualitylabelsall models Structure of the binding domain of the Metabotropic Glutamate Receptor, GluR1, bound to glutamateand gadolinium ions (1isr) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Articles in Proteopedia concerning Toll-like Receptors include:

• Leucine-rich repeat
• Membrane proteins

3D structures of metabotropic glutamate receptor

Metabotropic glutamate receptor 1

1ewt, 1ewv - rMGluR1 ligand-binding domain
3ks9 – hMGluR1 (mutant) + antagonist
1isr, 1ewk – rMGluR1 ligand-binding domain + Glu
1iss - rMGluR1 ligand-binding domain + antagonist

Metabotropic glutamate receptor 3

2e4u – hMGluR3 ligand-binding domain (mutant) + Glu
2e4v, 2e4w, 2e4x, 2e4y, 2e4z - hMGluR3 ligand-binding domain (mutant) + agonist

Metabotropic glutamate receptor 5

3lmk – hMGluR5 ligand-binding domain (mutant) + positive allosteric modulator + Glu

Metabotropic glutamate receptor 7

3mq4 – hMGluR7 ligand-binding domain + antagonist

See Also

[Membrane Channels & Pumps]]
Ionotropic_Glutamate_Receptors
Alzheimer's Disease

• Ligand Binding N-Terminal of Metabotropic Glutamate Receptors