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3tow
From Proteopedia
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{{STRUCTURE_3tow| PDB=3tow | SCENE= }} | {{STRUCTURE_3tow| PDB=3tow | SCENE= }} | ||
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===Crystal Structure of the MABP Domain of MVB12B of Human ESCRT-I Complex=== | ===Crystal Structure of the MABP Domain of MVB12B of Human ESCRT-I Complex=== | ||
| + | {{ABSTRACT_PUBMED_22232651}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/MB12B_HUMAN MB12B_HUMAN]] Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3tow]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3tow]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TOW OCA]. |
| - | [[Category: | + | |
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022232651</ref><references group="xtra"/><references/> | ||
| + | [[Category: Human]] | ||
[[Category: Boura, E.]] | [[Category: Boura, E.]] | ||
[[Category: Hurley, J H.]] | [[Category: Hurley, J H.]] | ||
Revision as of 08:57, 27 November 2013
Contents |
Crystal Structure of the MABP Domain of MVB12B of Human ESCRT-I Complex
Template:ABSTRACT PUBMED 22232651
Function
[MB12B_HUMAN] Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.
About this Structure
3tow is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA.
Reference
- Boura E, Hurley JH. Structural basis for membrane targeting by the MVB12-associated beta-prism domain of the human ESCRT-I MVB12 subunit. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1901-6. Epub 2012 Jan 9. PMID:22232651 doi:http://dx.doi.org/10.1073/pnas.1117597109
