2xrf
From Proteopedia
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| - | [[Image:2xrf.png|left|200px]] | ||
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{{STRUCTURE_2xrf| PDB=2xrf | SCENE= }} | {{STRUCTURE_2xrf| PDB=2xrf | SCENE= }} | ||
| + | ===Crystal structure of human uridine phosphorylase 2=== | ||
| - | == | + | ==Function== |
| - | + | [[http://www.uniprot.org/uniprot/UPP2_HUMAN UPP2_HUMAN]] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates. | |
==About this Structure== | ==About this Structure== | ||
| - | [[2xrf]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[2xrf]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XRF OCA]. |
==See Also== | ==See Also== | ||
*[[Myosin|Myosin]] | *[[Myosin|Myosin]] | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Uridine phosphorylase]] | [[Category: Uridine phosphorylase]] | ||
[[Category: Arrowsmith, C H.]] | [[Category: Arrowsmith, C H.]] | ||
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[[Category: Bountra, C.]] | [[Category: Bountra, C.]] | ||
[[Category: Collins, R.]] | [[Category: Collins, R.]] | ||
| - | [[Category: Consortium, Structural Genomics.]] | ||
[[Category: Edwards, A M.]] | [[Category: Edwards, A M.]] | ||
[[Category: Flodin, S.]] | [[Category: Flodin, S.]] | ||
Revision as of 09:01, 27 November 2013
Contents |
Crystal structure of human uridine phosphorylase 2
Function
[UPP2_HUMAN] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
About this Structure
2xrf is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA.
See Also
Categories: Human | Uridine phosphorylase | Arrowsmith, C H. | Berg, S Van Der. | Berglund, H. | Bountra, C. | Collins, R. | Edwards, A M. | Flodin, S. | Flores, A. | Graslund, S. | Hammarstrom, M. | Johansson, I. | Karlberg, T. | Kol, S. | Kotenyova, T. | Kouznetsova, E. | Moche, M. | Nordlund, P. | Nyman, T. | Persson, C. | Schuler, H. | Schutz, P. | Siponen, M I. | Thorsell, A G. | Tresaugues, L. | Wahlberg, E. | Weigelt, J. | Welin, M. | Transferase
