4jir
From Proteopedia
(Difference between revisions)
| Line 7: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[4jir]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[4jir]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JIR OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024100137</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024100137</ref><references group="xtra"/><references/> | ||
[[Category: Aldehyde reductase]] | [[Category: Aldehyde reductase]] | ||
| - | [[Category: | + | [[Category: Human]] |
[[Category: Chen, K.]] | [[Category: Chen, K.]] | ||
[[Category: Hu, X.]] | [[Category: Hu, X.]] | ||
Revision as of 09:04, 27 November 2013
Contents |
Crystal Structure Of Aldose Reductase (AKR1B1) Complexed With NADP+ And Epalrestat
Template:ABSTRACT PUBMED 24100137
Function
[ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
About this Structure
4jir is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA.
Reference
- Zhang L, Zhang H, Zhao Y, Li Z, Chen S, Zhai J, Chen Y, Xie W, Wang Z, Li Q, Zheng X, Hu X. Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111). FEBS Lett. 2013 Oct 4. pii: S0014-5793(13)00726-6. doi:, 10.1016/j.febslet.2013.09.031. PMID:24100137 doi:http://dx.doi.org/10.1016/j.febslet.2013.09.031
