4m9f

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4m9f| PDB=4m9f | SCENE= }}
 +
===Dengue virus NS2B-NS3 protease A125C variant at pH 8.5===
 +
{{ABSTRACT_PUBMED_24164286}}
-
The entry 4m9f is ON HOLD until Paper Publication
+
==Function==
 +
[[http://www.uniprot.org/uniprot/Q91H74_9FLAV Q91H74_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
-
Authors: Yildiz, M., Ghosh, S., Bell, J.A., Sherman, W., Hardy, J.A.
+
==About this Structure==
 +
[[4m9f]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9F OCA].
-
Description: Dengue virus NS2B-NS3 protease A125C variant at pH 8.5
+
==Reference==
 +
<ref group="xtra">PMID:024164286</ref><references group="xtra"/><references/>
 +
[[Category: Bell, J A.]]
 +
[[Category: Ghosh, S.]]
 +
[[Category: Hardy, J A.]]
 +
[[Category: Sherman, W.]]
 +
[[Category: Yildiz, M.]]
 +
[[Category: Allosteric inhibition]]
 +
[[Category: Conformational flexibility]]
 +
[[Category: Dengue virus protease]]
 +
[[Category: Serine protease]]
 +
[[Category: Trypsin-like protease]]
 +
[[Category: Viral protein]]

Revision as of 10:19, 27 November 2013

Template:STRUCTURE 4m9f

Contents

Dengue virus NS2B-NS3 protease A125C variant at pH 8.5

Template:ABSTRACT PUBMED 24164286

Function

[Q91H74_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]

About this Structure

4m9f is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4m9f"
Personal tools