SAGA-associated factor
From Proteopedia
(Difference between revisions)
(New page: <StructureSection load='3mhs' size='350' side='right' caption='Structure of SGF11 in the SAGA complex with Sus1, SGF73 and UB8P (PDB entry 3mhs)' scene=''> '''SAGA-associated fact...) |
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| - | + | <StructureSection load='3mhs' size='350' side='right' caption='Structure of SGF11 (pink) in the SAGA complex with Sus1 (green) , SGF73 (magenta), ubiquitin (yellow) and UB8P (grey) (PDB entry [[3mhs]])' scene=''> | |
| - | <StructureSection load='3mhs' size='350' side='right' caption='Structure of SGF11 in the SAGA complex with Sus1, SGF73 and UB8P (PDB entry [[3mhs]])' scene=''> | + | |
'''SAGA-associated factor''' (SGF) is part of the coactivator complex SAGA (Spt-Ada-Gcn5-Acetyl transferase) which facilitates transcription of stress-activated genes. SGF29 binds methylated lysine of histone H3 and is involved in transcriptional regulation. SGF11 is required for the deubiuqitination of histone H2B and for the maintenance of steady-state H3 methylation level. | '''SAGA-associated factor''' (SGF) is part of the coactivator complex SAGA (Spt-Ada-Gcn5-Acetyl transferase) which facilitates transcription of stress-activated genes. SGF29 binds methylated lysine of histone H3 and is involved in transcriptional regulation. SGF11 is required for the deubiuqitination of histone H2B and for the maintenance of steady-state H3 methylation level. | ||
==3D structures of SAGA-associated factor== | ==3D structures of SAGA-associated factor== | ||
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| + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
===SGF11=== | ===SGF11=== | ||
[[2lo2]] – ySGF zinc finger domain – yeast – NMR<br /> | [[2lo2]] – ySGF zinc finger domain – yeast – NMR<br /> | ||
| - | [3kik]], [[3kjl]] – ySGF Sus1-binding domain + Sus1 <br /> | + | [[3kik]], [[3kjl]] – ySGF Sus1-binding domain + Sus1 <br /> |
[[3mhh]], [[3m99]], [[4fip]], [[4fjc]], [[4fk5]] – yUBP8 + Sus1 +SGF73 - yeast<br /> | [[3mhh]], [[3m99]], [[4fip]], [[4fjc]], [[4fk5]] – yUBP8 + Sus1 +SGF73 - yeast<br /> | ||
[[3mhs]] – yUBP8 + Sus1 +SGF73 + ubiquitin<br /> | [[3mhs]] – yUBP8 + Sus1 +SGF73 + ubiquitin<br /> | ||
Revision as of 10:21, 27 November 2013
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