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4m9m

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'''Unreleased structure'''
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{{STRUCTURE_4m9m| PDB=4m9m | SCENE= }}
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===NS2B-NS3 protease from dengue virus at pH 8.5===
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{{ABSTRACT_PUBMED_24164286}}
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The entry 4m9m is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/Q91H74_9FLAV Q91H74_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
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Authors: Yildiz, M., Hardy, J.A.
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==About this Structure==
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[[4m9m]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M9M OCA].
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Description: NS2B-NS3 protease from dengue virus at pH 8.5
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==Reference==
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<ref group="xtra">PMID:024164286</ref><references group="xtra"/><references/>
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[[Category: Hardy, J A.]]
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[[Category: Yildiz, M.]]
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[[Category: Allosteric inhibition]]
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[[Category: Conformational flexibility]]
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[[Category: Dengue virus protease]]
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[[Category: Serine protease]]
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[[Category: Trypsin-like protease]]
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[[Category: Viral protease]]
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[[Category: Viral protein]]

Revision as of 10:24, 27 November 2013

Template:STRUCTURE 4m9m

Contents

NS2B-NS3 protease from dengue virus at pH 8.5

Template:ABSTRACT PUBMED 24164286

Function

[Q91H74_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]

About this Structure

4m9m is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

Proteopedia Page Contributors and Editors (what is this?)

OCA

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